LEK Exam: 2018 sesja jesienna, subject: Interna, question nr: 6

Indicate the false statement concerning proton-pump inhibitors (PPIs):

A. all PPIs must be taken 15-30 minutes before the morning meal.

B. mechanism of PPI action consists in an irreversible inhibition of H+/K+-ATPase of the gastric parietal cells.

C. chronic use of PPIs in patients with Helicobacter pylori infection may lead to atrophic gastritis.

D. PPIs increase moderately serum gastrin concentrations.

E. in patients with Zollinger-Ellison syndrome PPIs are recommended at a dose several fold higher than the standard one.

Dział: Interna