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108.

What is the most frequent adjustment of insulin dose needed in a type 1 diabetes patient as chronic kidney disease progresses to end-stage kidney disease?

A. insulin dose should be increased.
B. insulin dose should be decreased.
C. insulin dose should not be changed.
D. short acting insulin dose should be increased but long acting insulin dose should be decreased.
E. long acting insulin dose should be increased but short acting insulin dose should be decreased.

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