We offer access to questions covering the CEM database and LEK questions from 2008.
We offer access to archived PES questions from the CEM website and unpublished questions from the latest 5 years for selected specializations.
13.
Indicate the true information on Alport’s syndrome of sex-linked inheritance:
1) it is caused by inherited defect in alpha 5 collagen IV chain synthesis and leads to end-stage renal disease;
2) women (heterozygotes) are healthy gene carriers or they have only mild symptoms;
3) haematuria and proteinuria occur in men at around 10 years of age;
4) therapy with cyclosporine inhibits the development of the disease;
5) angiotensin converting enzyme inhibitors are used to decrease proteinuria.
The correct answer is: